Since 2026, the Hellenic Society of Basic and Clinical Pharmacology has partnered with Frontiers in Pharmacology to strengthen the dissemination of high-quality pharmacological research and foster scientific collaboration within our community.
As a key initiative of this partnership, the first two Research Topics proposed by HSBCP members have now launched on the journal’s website. These collections highlight cutting-edge research and provide a platform for experts to contribute to timely and impactful topics. We warmly invite you all to contribute to these collections.
Any HSBCP member interested in editing a Research Topic can contact an HSBCP Executive Board member or the point of contact for the Frontiers Research Topic shown below for more details.
Point of Contact for Frontiers Research Topic or agreement:
Chrysanthi Chatzopoulou, Senior Journal Manager
chrysa.chatzopoulou@frontiersin.org
Research Topic 1
Title: The Evolving Landscape of Omics-based Biomarkers in Precision Therapeutics
Topic Editors: Georgia Ragia, Evangelia Papadimitriou, Antonis Goulas, Vangelis Manolopoulos
This Research Topic welcomes Original Research, Reviews, Mini-Reviews, Methods, Perspectives, and Clinical Trial articles on themes including:
– Pharmacogenomics and pharmacotranscriptomics for predicting drug response, dosing, toxicity, and adverse drug reactions
– Multi-omics integration and AI/machine learning approaches for biomarker discovery, validation, drug repurposing, and clinical translation
– Emerging biomarker modalities: liquid biopsy, extracellular vesicles, epigenomic, and microbiome signatures
– Companion diagnostics, stratified medicine, and regulatory pathways to clinical implementation
– Biomarkers for advanced therapeutics — including cell, gene, and RNA-based therapies
Contributions that bridge fundamental discovery and clinical application are especially encouraged, as are studies addressing underrepresented populations, pediatric and geriatric pharmacology, and implementation experience from real-world health systems.
Together with HSBCP, this collection sets out to map where omics-based biomarkers are genuinely changing patient care and where the field still has work to do.
Link to Frontiers in Pharmacology Research Topic: Frontiers | The Evolving Landscape of Omics-based Biomarkers in Precision Therapeutics
Research Topic 2
Title: Targeting RNA Modifications as an Anti-cancer Approach
Topic Editors: Eugenia Yiannakopoulou, Andreas Papapetropoulos, Evangelia Papadimitriou, Konstantinos Xanthopoulos, Theodoros Sklaviadis
This Research Topic welcomes original research, reviews, and perspectives that address, but are not limited to, the following themes:
– Pharmacological targeting of dysregulated RNA modification enzymes (writers, erasers, readers) as a novel anticancer strategy
– Drug discovery and development of small-molecule inhibitors or activators of RNA modification machinery (e.g., ADAR, METTL3/14, FTO, ALKBH5)
– Pharmacogenomic implications of RNA modification profiles for predicting drug response and patient stratification in cancer
– Drug resistance mechanisms driven by aberrant RNA modifications (m⁶A, m⁵C, A-to-I editing, Ψ, ac⁴C) and strategies to overcome them
– Preclinical and translational studies evaluating RNA modification–targeted compounds in cancer models, including pharmacokinetics, pharmacodynamics, and efficacy data.
Link to Frontiers in Pharmacology Research Topic: Frontiers | Targeting RNA Modifications as an Anti-cancer Approach