{"id":2465,"date":"2026-09-25T16:05:37","date_gmt":"2026-09-25T13:05:37","guid":{"rendered":"https:\/\/hsbcp.gr\/?page_id=2465"},"modified":"2026-09-25T16:10:27","modified_gmt":"2026-09-25T13:10:27","slug":"zbrain-zebrafish-models-for-brain-cancer-treatment","status":"publish","type":"page","link":"https:\/\/hsbcp.gr\/el\/zbrain-zebrafish-models-for-brain-cancer-treatment\/","title":{"rendered":"zBRAIN: \u039c\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1 Zebrafish \u03b3\u03b9\u03b1 \u03c4\u03b7 \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u039a\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u0395\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5"},"content":{"rendered":"<div class=\"wpb-content-wrapper\" id=\"wpb-content-root\"><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div id=\"cz_21519\" class=\"cz_21519 cz_title clr cz_title_pos_inline\"><div class=\"cz_title_content\"><div class=\"cz_wpe_content\"><h4><strong>\u03a4\u03af\u03c4\u03bb\u03bf\u03c2:\u00a0<\/strong>\u00a0\u03a7\u03c1\u03ae\u03c3\u03b7 Zebrafish Avatars \u0391\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u039a\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u0395\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03a0\u03c1\u03cc\u03b2\u03bb\u03b5\u03c8\u03b7 \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u0395\u03ba\u03b2\u03ac\u03c3\u03b5\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b7 \u0394\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u039d\u03ad\u03c9\u03bd \u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03a0\u03c1\u03bf\u03c3\u03b5\u03b3\u03b3\u03af\u03c3\u03b5\u03c9\u03bd (zBRAIN)<\/h4>\n<\/div><\/div><\/div><div class=\"cz_gap clr\" style=\"height: 50px\"><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div id=\"cz_107234\" class=\"cz_107234 cz_title clr cz_title_pos_inline\"><div class=\"cz_title_content\"><div class=\"cz_wpe_content\"><p>\u0397 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 zBRAIN \u03c0\u03c1\u03bf\u03ac\u03b3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03bd\u03b5\u03c5\u03c1\u03bf-\u03bf\u03b3\u03ba\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03b1\u03be\u03b9\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03bf\u03c1\u03b8\u03bf\u03c4\u03bf\u03c0\u03b9\u03ba\u03ac \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1 \u03be\u03b5\u03bd\u03bf\u03bc\u03b5\u03c4\u03b1\u03bc\u03cc\u03c3\u03c7\u03b5\u03c5\u03c3\u03b7\u03c2 \u03b3\u03bb\u03bf\u03b9\u03bf\u03b2\u03bb\u03b1\u03c3\u03c4\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b1\u03c0\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c3\u03b5 zebrafish (\u00abZebrafish Avatars\u00bb)\u00a0<em>,<\/em>\u00a0\u03c9\u03c2 \u03bc\u03af\u03b1 \u03c4\u03b1\u03c7\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03c6\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae in vivo \u03c0\u03bb\u03b1\u03c4\u03c6\u03cc\u03c1\u03bc\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03c9\u03bd.<\/p>\n<p>\u03a4\u03bf \u03b3\u03bb\u03bf\u03b9\u03bf\u03b2\u03bb\u03ac\u03c3\u03c4\u03c9\u03bc\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03ad\u03bd\u03b1\u03bd \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03b9\u03b8\u03b5\u03c4\u03b9\u03ba\u03cc \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u03b5\u03b3\u03ba\u03b5\u03c6\u03ac\u03bb\u03bf\u03c5 \u03bc\u03b5 \u03b4\u03c5\u03c3\u03bc\u03b5\u03bd\u03ae \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ad\u03c2, \u03b1\u03bd\u03b1\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b5\u03af\u03b3\u03bf\u03c5\u03c3\u03b1 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03b3\u03b9\u03b1 \u03ba\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03b5\u03c2 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03bf\u03c3\u03b5\u03b3\u03b3\u03af\u03c3\u03b5\u03b9\u03c2.<\/p>\n<p><strong>\u03a4\u03bf zBRAIN<\/strong> \u03a4\u03bf zBRAIN \u03c3\u03c4\u03bf\u03c7\u03b5\u03cd\u03b5\u03b9 \u03bd\u03b1 \u03b3\u03b5\u03c6\u03c5\u03c1\u03ce\u03c3\u03b5\u03b9 \u03c4\u03bf \u03c7\u03ac\u03c3\u03bc\u03b1 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1\u03c2 \u03bc\u03ad\u03c3\u03c9 \u03b5\u03bd\u03cc\u03c2 \u00ab\u03c3\u03c5\u03bd-\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd\u00bb (co-clinical) \u03c0\u03bb\u03b1\u03b9\u03c3\u03af\u03bf\u03c5, \u03c3\u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03bd\u03b5\u03bf\u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03b8\u03ad\u03bd\u03c4\u03b5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b3\u03bb\u03bf\u03b9\u03bf\u03b2\u03bb\u03ac\u03c3\u03c4\u03c9\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b5\u03c0\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7 \u03b5\u03bd\u03c3\u03c9\u03bc\u03b1\u03c4\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf Zebrafish Avatar \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2. \u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1, \u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b8\u03b1 \u03b5\u03c6\u03b1\u03c1\u03bc\u03cc\u03c3\u03b5\u03b9 \u03bc\u03af\u03b1 \u03ba\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03bf \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae \u00ab\u03b4\u03b9\u03c0\u03bb\u03bf\u03cd \u03be\u03b5\u03bd\u03bf\u03bc\u03bf\u03c3\u03c7\u03b5\u03cd\u03bc\u03b1\u03c4\u03bf\u03c2\u00bb (double-xenograft), \u03bc\u03ad\u03c3\u03c9 \u03c3\u03c5\u03b3\u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 NK \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2 \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c4\u03b1 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1, \u03bc\u03b5 \u03c3\u03c4\u03cc\u03c7\u03bf \u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c4\u03c9\u03bd \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03c9\u03bd \u03cc\u03b3\u03ba\u03bf\u03c5\u2013\u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03c4\u03b9\u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03b5\u03bd\u03c4\u03cc\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b3\u03bb\u03bf\u03b9\u03bf\u03b2\u03bb\u03b1\u03c3\u03c4\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2. \u0395\u03c0\u03b9\u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b1, \u03c4\u03bf zBRAIN \u03b8\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd in vivo \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ce\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03bf\u03c3\u03b5\u03b3\u03b3\u03af\u03c3\u03b5\u03c9\u03bd \u03b2\u03b1\u03c3\u03b9\u03c3\u03bc\u03ad\u03bd\u03c9\u03bd \u03c3\u03b5 miRNA \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03bf\u03c5 \u03b3\u03bb\u03bf\u03b9\u03bf\u03b2\u03bb\u03b1\u03c3\u03c4\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2.\u00a0<em>,\u00a0<\/em>.<\/p>\n<p>\u03a7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c0\u03c1\u03bf\u03b7\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b6\u03c9\u03bd\u03c4\u03b1\u03bd\u03ae\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c3\u03c4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b1\u03c0\u03b5\u03b9\u03ba\u03cc\u03bd\u03b9\u03c3\u03b7\u03c2 (live confocal imaging), \u03c5\u03c8\u03b7\u03bb\u03ae\u03c2 \u03b1\u03c0\u03cc\u03b4\u03bf\u03c3\u03b7\u03c2<em>\u00a0,<\/em>\u00a0\u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bf\u03bb\u03c5\u03c0\u03b1\u03c1\u03b1\u03b3\u03bf\u03bd\u03c4\u03b9\u03ba\u03ae \u03b5\u03bd\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03c3\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ce\u03bd \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03bc\u03b5 \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b2\u03b9\u03bf\u03c3\u03c4\u03b1\u03c4\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03b2\u03b9\u03bf\u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7\u03c2, \u03c4\u03bf zBRAIN \u03b8\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03ae\u03c3\u03b5\u03b9 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5, \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7, \u03b7 \u03b4\u03b9\u03ae\u03b8\u03b7\u03c3\u03b7, \u03b7 \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03af \u03c6\u03b1\u03b9\u03bd\u03cc\u03c4\u03c5\u03c0\u03bf\u03b9, \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03b4\u03c5\u03bd\u03b1\u03bc\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03b1\u03bd\u03b1\u03bb\u03c5\u03cc\u03bc\u03b5\u03bd\u03bf \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd, \u03bc\u03b5 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c0\u03c1\u03cc\u03b8\u03b5\u03c3\u03bc\u03bf \u03c3\u03c4\u03cc\u03c7\u03bf \u03c4\u03b7\u03bd \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03b2\u03bb\u03b5\u03c0\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03c9\u03bd zebrafish avatars \u03c9\u03c2 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b9\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b5\u03ba\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd.<\/p>\n<\/div><\/div><\/div><div class=\"cz_gap clr\" style=\"height: 50px\"><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div id=\"cz_97393\" class=\"cz_97393 cz_title clr cz_title_pos_inline\"><div class=\"cz_title_content\"><div class=\"cz_wpe_content\"><h3>\u0399\u03c3\u03c4\u03bf\u03c3\u03b5\u03bb\u03af\u03b4\u03b1:\u00a0<a href=\"http:\/\/www.dietislab.org\/zbrain\">www.dietislab.org\/zbrain<\/a><\/h3>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"Project title:\u00a0\u00a0Using Zebrafish Avatars of BRAIN Cancer Patients to Predict Therapeutic Outcomes and \u200bExplore Novel Therapies (zBRAIN) The zBRAIN 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